Time-lapse in the IVF-lab: how should we assess potential benefit?
- PMID: 25316446
- DOI: 10.1093/humrep/deu250
Time-lapse in the IVF-lab: how should we assess potential benefit?
Abstract
Time-lapse imaging of embryos has been widely introduced to fertility laboratories worldwide with the aim of identifying the best quality embryos to transfer that will ultimately improve IVF success rates. In this opinion paper, we explore the lack of evidence of benefit of this novel intervention, analyse the methodological flaws of current studies, offer ideal study designs that assess the various features of time-lapse imaging, and discuss forthcoming studies. In particular, we emphasize the ethical aspects of hastily adopting a costly technology without current high level evidence of improved live birth rates, safety and cost effectiveness.
Keywords: IVF; IVF outcome; embryo incubation; live birth; time-lapse.
© The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Comment in
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Reply: time-lapse in the IVF lab: how should we assess potential benefit?Hum Reprod. 2015 May;30(5):1277. doi: 10.1093/humrep/dev046. Epub 2015 Mar 6. Hum Reprod. 2015. PMID: 25750206 No abstract available.
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Time-lapse in the IVF lab: how should we assess potential benefit?Hum Reprod. 2015 May;30(5):1276. doi: 10.1093/humrep/dev045. Epub 2015 Mar 6. Hum Reprod. 2015. PMID: 25750207 No abstract available.
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