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. 2014 Oct;18(10):659-65.
doi: 10.4103/0972-5229.142175.

Incidence and outcome of acute lung injury and acute respiratory distress syndrome in the surgical intensive care unit

Georgene Singh  1 , George Gladdy  1 , Tony Thomson Chandy  1 , Nagamani Sen  2
Affiliations

Incidence and outcome of acute lung injury and acute respiratory distress syndrome in the surgical intensive care unit

Georgene Singh et al. Indian J Crit Care Med. 2014 Oct.

Abstract

Introduction: To determine the incidence and mortality of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in a cohort of patients with risk factors admitted to the Surgical Intensive Care Unit (SICU).

Materials and methods: A prospective observational inception cohort study with no intervention was conducted over 12 months. All patients with at least one known risk factor for ALI/ARDS admitted to the SICU were included in the study. The APACHE II severity of disease classification system scoring was performed within 1 h of admission. The ventilatory parameters and chest radiographs were recorded every 24 h. The P/F ratio, PEEP and Lung Injury Score were calculated each day until the day of discharge from the Intensive Care Unit or for the first 7 days of admission, whichever was shorter.

Results: The incidence of ARDS among those who were mechanically ventilated was 11.4%. Sepsis was the most common (34.6%) etiology. Among those with risk factors, the incidence of ARDS was 30% and that of ALI was 32.7%. The mortality in those with ARDS was 41.8%. Those who develop ARDS had higher APACHE II scores, lower pH and higher PaCO2 at admission compared with those who developed ALI or no lung injury.

Conclusion: The incidence and mortality of ARDS was similar to other studies. Identifying those with risk factors for ARDS or mortality will enable appropriate interventional measures.

Keywords: Acute lung injury; acute respiratory distress syndrome; incidence; mortality.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Pattern of P/F ratio among survivors and non-survivors of acute respiratory distress syndrome
Figure 2
Figure 2
Pattern of radiological injury among survivors and non-survivors of acute respiratory distress syndrome
Figure 3
Figure 3
Pattern of lung injury score among survivors and non-survivors of acute respiratory distress syndrome
Figure 4
Figure 4
Pattern of PEEP among survivors and non-survivors of acute respiratory distress syndrome
See this image and copyright information in PMC

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