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Review
. 1989 Oct;21(5):605-20.
doi: 10.1007/BF00808116.

Vacuolar proton pumps

D K Stone  1 , B P Crider, T C Südhof, X S Xie
Affiliations
Review

Vacuolar proton pumps

D K Stone et al. J Bioenerg Biomembr. 1989 Oct.

Abstract

Recently a new class of proton-translocating ATPases has been localized to endomembrane compartments in plant, fungal, and mammalian cells. These proton pumps are large hetero-oligomers which have an ATP hydrolytic sector that is functionally and structurally distinct from a transmembranous proton pore. Enzymatic characteristics of these proton pumps are discussed as well as the current state of knowledge regarding subunit composition and function. In addition, recent primary sequence data are discussed which indicate that these proton pumps share a common ancestor with F1F0-type proton pumps of mitochondria.

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References

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