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. 1989 Nov;24(6):362-7.
doi: 10.1111/j.1600-0765.1989.tb00883.x.

Increased interleukin-1 beta (IL-1 beta) concentration in gingival tissue from periodontitis patients

J Hönig, C Rordorf-Adam, C Siegmund, W Wiedemann, F Erard

Increased interleukin-1 beta (IL-1 beta) concentration in gingival tissue from periodontitis patients

J Hönig et al. J Periodontal Res. 1989 Nov.

Abstract

Human gingival tissues from periodontitis patients were found to contain from 126 fg/mg to 2161 fg/mg interleukin-1 beta as determined by a sensitive enzyme linked immunoassay. No IL-1 beta could be found in normal gingival tissue. This finding may have important consequences relevant to connective tissue destruction and episodes of alveolar bone resorption characteristic of chronic periodontitis.

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