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Multicenter Study
. 2014 Jun;14(2):446-52.
doi: 10.4314/ahs.v14i2.22.

Stroke prevalence amongst sickle cell disease patients in Nigeria: a multi-centre study

Madu Anazoeze Jude  1 , Galadanci Najiba Aliyu  2 , Aisha Mohammed Nalado  2 , Kangiwa Umar Garba  3 , Fowodu O Florence  4 , Ahmed Hassan  5 , Marcus Inyama  6 , Oluwaseun Akinpelu  7 , Nwagha Theresa  1 , Ibegbulam Obike Godswill  1 , Ocheni Sunday  1 , Emodi Ifeoma  8 , Ikefuna Anthony  8 , Chukwu Batholomew  8 , Okocha E Chide  9 , Orkuma Joseph  10 , Iheanacho Malachy  11 , Kaladada Korubo  12 , Anike Uchenna Sabastine  13 , Agu Kingsley  13 , Charles Nonyelu  13 , Angela Ugwu  13 , Augustin Duru  13 , Chukwudi Anigbo  13 , Alozie Eze  13 , Awele Chukwurah  13 , Uchenna Ololo  13 , Caroline Omoti  14 , Obineche Agwu  13 , Okpala Iheanyi  13
Affiliations
Multicenter Study

Stroke prevalence amongst sickle cell disease patients in Nigeria: a multi-centre study

Madu Anazoeze Jude et al. Afr Health Sci. 2014 Jun.

Abstract

Background: Stroke is a life-changing, debilitating complication of sickle cell disease (SCD). Previous studies had recorded high stroke prevalence amongst this group of patients. Nigeria has a large population of people affected by this condition and this study aims to assess the stroke prevalence in this large population.

Methodology: Stroke prevalence data from 14 physicians working in 11 tertiary health centres across the country was collated by doctors using the sickle cell registers and patient case notes. This data was then collated and used to obtain the overall stroke prevalence in adult and children.

Results: The stroke prevalence in sickle cell disease patients in Nigeria was observed to be 12.4 per 1000 patients. Prevalence in the adult patients was 17.7 per 1000 patients and 7.4 per 1000 patients in children. Twenty three percent of the affected patients had more than stroke episode.

Conclusion: The stroke prevalence in Nigeria is lower than previously recorded rates and further studies will be required to investigate other factors which may play a role.

Keywords: Nigeria; prevalence; sickle cell; stroke.

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Figures

Figure 1
Figure 1
Distribution of patients recorded in tertiary health institutions across Nigeria
Figure 2
Figure 2
Frequency distribution of number of patients who had stroke across the participating centers
Figure 3
Figure 3
Frequency distribution of the number of patients who had more than one stroke in Tertiary health institutions recorded
Figure 4
Figure 4
Prevalence Map of stroke in patients with SCD in Nigeria
See this image and copyright information in PMC

References

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