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. 2014 Oct 20:2014:0506.

Tinnitus

Julian Savage  1 , Angus Waddell
Affiliations

Tinnitus

Julian Savage et al. BMJ Clin Evid. .

Abstract

Introduction: Up to 18% of people in industrialised societies are mildly affected by chronic tinnitus, and 0.5% report tinnitus having a severe effect on their daily life. Tinnitus can be associated with hearing loss, acoustic neuromas, drug toxicity, ear diseases, and depression. Tinnitus can last for many years, and can interfere with sleep and concentration.

Methods and outcomes: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for chronic tinnitus? We searched: Medline, Embase, The Cochrane Library, and other important databases up to November 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).

Results: We found 33 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.

Conclusions: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: acamprosate, acupuncture, antidepressant drugs, benzodiazepines, carbamazepine, electromagnetic stimulation, ginkgo biloba, hearing aids, hypnosis, psychotherapy, tinnitus-masking devices, and cognitive behavioural therapy plus tinnitus-masking device (tinnitus retraining therapy).

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References

    1. Coles RR. Epidemiology of tinnitus: (1) prevalence. J Laryngol Otol 1984;9(suppl):7–15. - PubMed
    1. Sullivan MD, Katon W, Dobie R, et al. Disabling tinnitus: association with affective disorder. Gen Hosp Psychiatry 1988;10:285–291. - PubMed
    1. Zoger S, Svedlund J, Holgers KM. Psychiatric disorders in tinnitus patients without severe hearing impairment: 24 month follow-up of patients at an audiological clinic. Audiology 2001;40:133–140. - PubMed
    1. Pichora-Fuller MK, Santaguida P, Hammill A, et al; Agency for Healthcare Research and Quality. Evaluation and treatment of tinnitus: comparative effectiveness. August 2013. Available at http://effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-report... (accessed on 25 July 2014). - PubMed
    1. Sharma DK, Kaur S, Singh J, et al. Role of acamprosate in sensorineural tinnitus. Ind J Pharmacol 2012;44:93–96. - PMC - PubMed

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