Oral cavity squamous cell carcinoma - characteristics and survival in aboriginal and non-aboriginal Western australians

Abstract

Background: Squamous cell carcinoma (SCC) is the most common type of malignancy affecting the oral cavity. While exposures to main risk factors for oral SCC such as smoking and alcohol use are higher amongst the Aboriginal people, little is known about oral cancer in this population. This study aimed to describe characteristics and survival of oral SCC in Aboriginal and non-Aboriginal Western Australians.

Methods: All primary oral SCC cases reported to the Western Australian Cancer Registry (WACR) between 1990 and 1999 were analysed with respect to person characteristics including: date of birth, sex and indigenous status; and disease characteristics including: date of biopsy, disease stage and site as well as date of recurrence and date of death. Exclusion criteria included diagnosis not based on incisional or excisional biopsy, diagnosis other than oral SCC or a history of another malignant neoplasm.

Results: Aboriginal individuals were more likely to reside in rural areas. No statistically significant differences in oral SCC characteristics and survival were noted between Aboriginal and non-Aboriginal Western Australians.

Conclusion: This study provides new information on person and disease characteristics of Aboriginal Western Australians diagnosed with oral SCC.

Keywords: Aboriginality; epidemiology; oral cancer; survival analysis..

Fig. (1)

Kaplan-Meier curves for Aboriginal and non-Aboriginal status. The outcome is time (years) from initial biopsy to cancer related death or recurrence.

Fig. (2)

Kaplan-Meier curves for Aboriginal and non-Aboriginal status. The outcome is time (years) from initial biopsy to cancer related death.

Fig. (3)

Kaplan-Meier curves for Aboriginal and non-Aboriginal status. The outcome is time (years) from initial biopsy to death from any cause.