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Transplant associated thrombotic microangiopathy is a severe complication of Hematopoeitic stem cell transplantation. Although there is agreement in terms of diagnostic criteria, treatment options are not clarified yet. We present a patient aged 2.6 years who developed transplant associated thrombotic microangiopathy after allogeneic bone marrow transplantation and to discuss both risk factors and possible spontaneous remission of transplant associated thrombotic microangiopathy.
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Uderzo C, Bonanomi S, et al. Risk factors and severe outcome in Thrombotic Microangiopathy after allogeneic hematopoetic stem cell transplantation. Transplantation. 2006;82:638. doi: 10.1097/01.tp.0000230373.82376.46.
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Cutler C, Henry NL, Magee C, et al. Sirolimus and thrombotic microangiopathy after allogeneic hematopoetic stem cell transplantation. Biol Blood Marrow Transpl. 2005;11:551–557. doi: 10.1016/j.bbmt.2005.04.007.
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Stavrou E, Lazarus HM. Thrombotic microangiopathy in hematopoetic cell transplantation: an update. Mediterr J Hemat Infect Dis. 2010;2(3):e 2010033. doi: 10.4084/mjhid.2010.033.
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Shimoni, et al. Thrombotic microangiopathy after allogeneic stem cell transplantation in the era of reduced intensity conditioning. The incidence is not reduced. Biol Blood Marrow Transpl. 2004;10:484. doi: 10.1016/j.bbmt.2004.03.002.
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