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Case Reports
. 2014 Sep;30(Suppl 1):390-3.
doi: 10.1007/s12288-014-0430-0. Epub 2014 Jul 4.

Primary plasma cell leukaemia with unusual presentations: a case series

Urmila Majhi  1 , Kanchan Murhekar  1 , Shirley Sundersingh  1 , K R Rajalekshmi  1
Affiliations
Case Reports

Primary plasma cell leukaemia with unusual presentations: a case series

Urmila Majhi et al. Indian J Hematol Blood Transfus. 2014 Sep.

Abstract

We present here three cases of plasma cell dyscrasias; first case presenting as primary plasma cell leukemia showing unusual morphology and aberrant expression of myeloid markers; the second case presenting as plasma cell leukaemia with atypical plasma cells in peripheral blood and the third case presenting as myelomatous pleural effusion after treatment for myeloma.

Keywords: Aberrant expression; Myeolomatous pleural effusion; Plasma cell leukemia.

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Figures

Fig. 1
Fig. 1
a H&E×40. Bone marrow biopsy showing atypical plasma cells. b IHC ×40. Bone marrow showing CD 43 positivity. c IHC ×40. Bone marrow biopsy showing CD 138 positivity. d Leishman’s stain ×100. Bone marrow smear showing atypical plasma cells with unusual morphology. Binucleated, multinucleated and multi lobulated plasma cells are seen
Fig. 2
Fig. 2
a Leishman’s stain ×100. Bone marrow smear showing atypical plasma cells with abundant basophilic cytoplasm and prominent nucleoli. b Leishman’s smear ×100. Peripheral smear shows abnormal plasma cells
Fig. 3
Fig. 3
a H&E ×40: chest wall tumour showing abnormal plasma cells. b IHC ×40: abnormal plasma cells showing CD 138 positivity. c H&E ×100: bone marrow biopsy showing atypical plasma cells. d Pap smear ×100: pleural fluid showing abnormal plasma cells. Bi and multinucleated forms are seen. Inset shows abnormal (tetrapolar) mitosis
See this image and copyright information in PMC

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