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. 2014 Oct 21;11(10):e1001747.
doi: 10.1371/journal.pmed.1001747. eCollection 2014 Oct.

How to make more published research true

John P A Ioannidis  1
Affiliations

How to make more published research true

John P A Ioannidis. PLoS Med. .

Abstract

In a 2005 paper that has been accessed more than a million times, John Ioannidis explained why most published research findings were false. Here he revisits the topic, this time to address how to improve matters. Please see later in the article for the Editors' Summary.

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Conflict of interest statement

JPAI is a member of the Editorial Board of PLOS Medicine. The author has declared that no competing interests exist.

References

    1. Boyack KW, Klavans R, Sorensen AA, Ioannidis JP (2013) A list of highly influential biomedical researchers, 1996–2011. Eur J Clin Invest 43: 1339–1365. - PubMed
    1. Ioannidis JP (2008) Why most discovered true associations are inflated. Epidemiology 19: 640–648. - PubMed
    1. Ioannidis JP (2005) Why most published research findings are false. PLoS Med 2: e124. - PMC - PubMed
    1. Contopoulos-Ioannidis DG, Alexiou GA, Gouvias TC, Ioannidis JP (2008) Life cycle of translational research for medical interventions. Science 321: 1298–1299. - PubMed
    1. Macleod MR, Michie S, Roberts I, Dirnagl U, Chalmers I, et al. (2014) Biomedical research: increasing value, reducing waste. Lancet 383: 101–104. - PubMed

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