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Case Reports
. 2014 Nov;20(11):1957-9.
doi: 10.3201/eid2011.141175.

Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi

Nicholas A Feasey, Amy K Cain, Chisomo L Msefula, Derek Pickard, Maaike Alaerts, Martin Aslett, Dean B Everett, Theresa J Allain, Gordon Dougan, Melita A Gordon, Robert S Heyderman, Robert A Kingsley
Case Reports

Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi

Nicholas A Feasey et al. Emerg Infect Dis. 2014 Nov.
No abstract available

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Figures

Figure
Figure
Midpoint-rooted phylogenetic tree of published whole-genome sequence data from D23580-like Salmonella enterica serotype Typhimurium sequence type 313s from Malawi based on 204 informative single-nucleotide polymorphisms. A54285 and A54560, highlighted in yellow on a red branch, are indistinguishable. Scale bar indicates nucleotide substitutions per site.
See this image and copyright information in PMC

References

    1. Feasey NA, Dougan G, Kingsley RA, Heyderman RS, Gordon MA. Invasive non-typhoidal Salmonella disease: an emerging and neglected tropical disease in Africa. Lancet. 2012;379:2489–99. 10.1016/S0140-6736(11)61752-2 - DOI - PMC - PubMed
    1. Okoro CK, Kingsley RA, Quail MA, Kankwatira AM, Feasey NA, Parkhill J, et al. High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and reinfection in recurrent invasive nontyphoidal Salmonella Typhimurium disease. Clin Infect Dis. 2012;54:955–63 . 10.1093/cid/cir1032 - DOI - PMC - PubMed
    1. Gordon MA, Banda HT, Gondwe M, Gordon SB, Boeree MJ, Walsh AL, et al. Non-typhoidal Salmonella bacteraemia among HIV-infected Malawian adults: high mortality and frequent recrudescence. AIDS. 2002;16:1633–41 . 10.1097/00002030-200208160-00009 - DOI - PubMed
    1. Gordon MA, Graham SM, Walsh AL, Wilson L, Phiri A, Molyneux E, et al. Epidemics of invasive Salmonella enterica serovar Enteritidis and S. enterica serovar Typhimurium infection associated with multidrug resistance among adults and children in Malawi. Clin Infect Dis. 2008;46:963–9. 10.1086/529146 - DOI - PubMed
    1. Kingsley RA, Msefula CL, Thomson NR, Kariuki S, Holt KE, Gordon MA, et al. Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. Genome Res. 2009;19:2279–87. 10.1101/gr.091017.109 - DOI - PMC - PubMed

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