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. 2014:2014:753149.
doi: 10.1155/2014/753149. Epub 2014 Sep 29.

Localised leishmaniasis of oral mucosa: report of an unusual clinicopathological entity

Deepak Passi  1 , Sarang Sharma  2 , Shubharanjan Dutta  3 , Chandan Gupta  4
Affiliations

Localised leishmaniasis of oral mucosa: report of an unusual clinicopathological entity

Deepak Passi et al. Case Rep Dent. 2014.

Abstract

The term leishmaniasis comprises of a group of diseases caused by different species of a protozoan called Leishmania. There are three main clinical forms of leishmaniasis: visceral leishmaniasis, cutaneous leishmaniasis, and mucocutaneous leishmaniasis. Exclusive involvement of the mucosa is very rare. We present a case of mucosal leishmaniasis located in the oral cavity. The only manifestation of leishmaniasis disease in the described case was the appearance of an oral lesion. Treatment was provided in the form of antimoniates (oral miltefosine and systemic sodium stibogluconate). A review of literature is made on the subject.

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Figures

Figure 1
Figure 1
Profile view showing no cutaneous lesion.
Figure 2
Figure 2
Involvement of labial mucosa and gingival hypertrophy with bleeding.
Figure 3
Figure 3
Involvement of hard and soft palate (cobblestone appearance of mucosa of the hard palate).
Figure 4
Figure 4
Histology of the oral lesion showing macrophages containing numerous Leishman bodies.
Figure 5
Figure 5
Giemsa staining shows numerous amastigotes with round nucleus.
Figure 6
Figure 6
Healing of lesion.
See this image and copyright information in PMC

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