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Review
. 2014;127(1-4):15-20.
doi: 10.1159/000363708. Epub 2014 Sep 24.

Effects of aging on renal function and regenerative capacity

Emaad M Abdel-Rahman  1 , Mark D Okusa
Affiliations
Review

Effects of aging on renal function and regenerative capacity

Emaad M Abdel-Rahman et al. Nephron Clin Pract. 2014.

Abstract

Along with the increase in aging of our population, the proportion of older patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) is on the rise as a result of the accumulation of comorbidities as well as biological processes associated with aging. Older patients with acute kidney injury (AKI) comprise an increasing proportion of patients with CKD/ESRD as well. In this review, we will discuss biological processes of aging that predispose patients to AKI and CKD.

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