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Comment
. 2015 Mar;70(3):954-6.
doi: 10.1093/jac/dku428. Epub 2014 Oct 23.

SAMHD1 expression in blood cells of HIV-1 elite suppressors and viraemic progressors

Erin L Buchanan  1 , Melissa A McAlexander  1 , Kenneth W Witwer  2
Affiliations
Comment

SAMHD1 expression in blood cells of HIV-1 elite suppressors and viraemic progressors

Erin L Buchanan et al. J Antimicrob Chemother. 2015 Mar.
No abstract available

Keywords: IFN; PBMCs; elite controllers; interferon.

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Figures

Figure 1.
Figure 1.
MX1 and SAMHD1 expression and correlation with viral load. HIV-1-positive VP, but not ES, displayed significantly higher levels of the type I IFN-responsive antiviral MX1 according to a Kruskal–Wallis test followed by post-tests (a); *P < 0.05. No differences were detected for retroviral restriction factor SAMHD1 (b). Within the VP group, there was an apparent trend towards negative correlation of both MX1 and SAMHD1 with viral load (c).
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References

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