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. 2014 Mar;8(1):42-4.
doi: 10.5704/MOJ.1403.017.

'Does the National Antibiotic Guideline- 2008 remain applicable for treating diabetic foot infection?' A new evidence-based regional study on culture and sensitivity patterns in Terengganu population

Sd Balakrishnan  1 , Nj Shahid  1 , Tm Fairuz  1 , Ima Ramdhan  1
Affiliations

'Does the National Antibiotic Guideline- 2008 remain applicable for treating diabetic foot infection?' A new evidence-based regional study on culture and sensitivity patterns in Terengganu population

Sd Balakrishnan et al. Malays Orthop J. 2014 Mar.

Abstract

Diabetic foot infections make up a significant number of orthopaedic ward admissions. The recommended choice of empirical antibiotics used in Malaysia for diabetic foot infections is based on the National Antibiotic Guidelines 2008. The pattern of bacteriology and the effectiveness of the treatment of diabetic foot infections based on this guideline were analyzed through a retrospective study in our hospital. Data over a period of one year (May 2012- April 2013) was analyzed, and 96 patients were included in this study. Polymicrobial growth (58%) was mainly isolated, followed with an almost equal percentage of gram-negative (22%) and gram-positive organisms (20%). The empirical antibiotics based on the national antibiotic guidelines were used as definitive antibiotics in 85% of the cases. Although there was slight variation in the pattern of organisms as compared to other studies conducted in this country, the high rate of positive clinical response proved that the antibiotic guideline was still effective in diabetic foot infection treatment.

Key words: Diabetic foot infections, National Antibiotic Guidelines, Culture and Sensitivity.

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Figures

<b>Table I</b>: Summarized National Antibiotic Guideline 2008 [4]
Table I: Summarized National Antibiotic Guideline 2008 [4]
<b>Table II</b>: Duration of diabetes
Table II: Duration of diabetes
<b>Table III</b>: Spectrum of monomicrobials isolated
Table III: Spectrum of monomicrobials isolated
<b>Figure I</b>: Overall pattern of microbials isolated.
Figure I: Overall pattern of microbials isolated.
<b>Figure II</b>: The response of patients to treatment based on National Antibiotic Guidelines 2008.
Figure II: The response of patients to treatment based on National Antibiotic Guidelines 2008.
See this image and copyright information in PMC

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