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. 2015 Jan;59(1):698-701.
doi: 10.1128/AAC.02415-14. Epub 2014 Oct 27.

Association of class 1 and 2 integrons with multidrug-resistant Acinetobacter baumannii international clones and Acinetobacter nosocomialis isolates

Natacha Martins  1 , Renata Cristina Picão  1 , Sheila Adams-Sapper  2 , Lee W Riley  2 , Beatriz Meurer Moreira  3
Affiliations

Association of class 1 and 2 integrons with multidrug-resistant Acinetobacter baumannii international clones and Acinetobacter nosocomialis isolates

Natacha Martins et al. Antimicrob Agents Chemother. 2015 Jan.

Abstract

The Acinetobacter baumannii clonal complex 113/79 (CC113/79) and class 2 integrons predominate in Latin America; a relationship between these characteristics was explored. The presence of integrases was determined in successive hospital Acinetobacter isolates (163 A. baumannii isolates and 72 Acinetobacter nosocomialis isolates). Most isolates had integrons, but class 1 and 2 integrons were present significantly more often in CC109/1 and CC113/79, respectively. The high prevalence of CC113/79 in Latin America may account for the predominance of class 2 integrons.

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Figures

FIG 1
FIG 1
Distribution of intI genes among A. baumannii and A. nosocomialis isolates.
FIG 2
FIG 2
Frequency of intI genes in 163 Acinetobacter baumannii isolates according to MLST clonal complexes (CC) (A) and 72 Acinetobacter nosocomialis isolates according to RAPD types (B). The white and black columns are intI1- and intI2-positive isolates, respectively. The asterisk in panel A represents a P value of <0.001 (compared to A. baumannii isolates included in all other clonal types), and that in panel B represents a P value of 0.02 (for intI1 in A. nosocomialis type C compared to type A).
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