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. 2015 Jan;59(1):714-6.
doi: 10.1128/AAC.04306-14. Epub 2014 Oct 27.

Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward

Eva Leitner  1 , Gernot Zarfel  1 , Josefa Luxner  1 , Kathrin Herzog  2 , Shiva Pekard-Amenitsch  3 , Martin Hoenigl  4 , Thomas Valentin  4 , Gebhard Feierl  1 , Andrea J Grisold  1 , Christoph Högenauer  2 , Heinz Sill  5 , Robert Krause  4 , Ines Zollner-Schwetz  6
Affiliations

Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward

Eva Leitner et al. Antimicrob Agents Chemother. 2015 Jan.

Abstract

We investigated sinks as possible sources of a prolonged Klebsiella pneumonia carbapenemase (KPC)-producing Klebsiella oxytoca outbreak. Seven carbapenem-resistant K. oxytoca isolates were identified in sink drains in 4 patient rooms and in the medication room. Investigations for resistance genes and genetic relatedness of patient and environmental isolates revealed that all the isolates harbored the blaKPC-2 and blaTEM-1 genes and were genetically indistinguishable. We describe here a clonal outbreak caused by KPC-2-producing K. oxytoca, and handwashing sinks were a possible reservoir.

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