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. 2014 Nov-Dec;56(6):505-10.
doi: 10.1590/s0036-46652014000600009.

Evaluation of the molluscicidal potential of hydroalcoholic extracts of Jatropha gossypiifolia Linnaeus, 1753 on Biomphalaria glabrata (Say, 1818)

Adalberto Alves Pereira Filho  1 , Clícia Rosane Costa França  1 , Dorlam's da Silva Oliveira  1 , Renato Juvino de Aragão Mendes  1 , José de Ribamar Santos Gonçalves  1 , Ivone Garros Rosa  1
Affiliations

Evaluation of the molluscicidal potential of hydroalcoholic extracts of Jatropha gossypiifolia Linnaeus, 1753 on Biomphalaria glabrata (Say, 1818)

Adalberto Alves Pereira Filho et al. Rev Inst Med Trop Sao Paulo. 2014 Nov-Dec.

Abstract
in English, Portuguese

The action of extracts from the stem, leaves, and fruit of Jatropha gossypiifolia on Biomphalaria glabrata was studied by analyzing survival, feeding capacity and oviposition ability. The extracts were obtained by macerating the plant parts in 92% ethanol, which were then evaporated until a dry residue was obtained and phytochemically studied. The molluscicidal activity on B. glabrata was investigated using the procedures recommended by WHO (1965). The amount of food ingested and oviposition were measured during each experiment. The extract of leaves from J. gossypiifolia was shown to be a strong molluscicidal agent, causing 100% mortality of B. glabrata, even in the lowest concentration tested, of 25 ppm. Regarding the fruit extract, there was variation in the mortality, depending on the concentration used (100, 75, 50 and 25 ppm). The snails that were in contact with the fruit extract had significant reduction in feeding and number of embryos in comparison to the control. The stem extract did not present molluscicidal activity nor had any influence on the feeding and oviposition abilities of B. glabrata, in the concentrations tested. In conclusion, the extracts of leaves and fruits of J. gossypiifolia investigated in this work show molluscicidal effect and may be sources of useful compounds for the schistosomiasis control.

Estudou-se a ação dos extratos do caule, folhas e frutos de Jatropha gossypiifolia (Pinhão-roxo) sobre Biomphalaria glabrata analisando a sobrevivência, capacidade alimentar e de oviposição. Os extratos foram obtidos pela maceração das partes do vegetal em álcool etílico 92%, evaporados até obter-se um resíduo seco e estudados fitoquimicamente. A atividade moluscicida em B. glabrata seguiu os procedimentos recomendados pela WHO (1965). A medida de quantidade de alimento ingerido e a oviposição foi realizada durante cada experimento. O extrato das folhas de J. gossypiifolia mostrou-se um forte agente moluscicida, promovendo 100% de mortalidade de B. glabrata mesmo na menor concentração testada, 25 ppm. Com o extrato dos frutos houve variação na mortalidade, de acordo com a concentração utilizada (100, 75, 50 e 25 ppm). Os caramujos em contato com o extrato dos frutos apresentaram quando comparado ao controle uma diminuição significativa nos comportamentos alimentares e de número de embriões. O extrato do caule não apresentou atividade moluscicida e nenhuma influência sobre a capacidade alimentar e de oviposição de B. glabrata nas concentrações testadas. Em conclusão, os extratos de folhas e frutos de J. gossypiifolia investigados neste trabalho apresentam efeito moluscicida e possivelmente podem ser fontes de compostos no controle da esquistossomose.

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Figures

Fig. 1
Fig. 1. Regression analysis of the concentrations of the Jatropha gossypiifolia fruit extracts versus the percentage of survival of Biomphalaria glabrata.
See this image and copyright information in PMC

References

    1. Abreu IC, Marinho ASS, Paes AMA, Freire SMF, Olea RS, Borges MOR, et al. Hypotensive and vasorelaxant effects of ethanolic extract from Jatropha gossypiifolia L. in rats. Fitoterapia. 2003;73:650–7. - PubMed
    1. Adewunmi CO. Natural products as agents of schistosomiasis control in Nigeria: a review of progress. Int J Crude Drug Res. 1984;22:161–6.
    1. Andrews P, Thyssen J, Lorke D. The biology and toxicology of molluscicides, Bayluscide. Pharmacol Ther. 1982;19:245–95. - PubMed
    1. Brasil . 2a ed. Brasília: Editora do Ministério da Saúde; 2008. Ministério da Saúde. Vigilância e controle de moluscos de importância epidemiológica: diretrizes técnicas. Programa de Vigilância e Controle da Esquistossomose (PCE)
    1. Cantanhede SPD, Marques AM, Silva-Souza N, Valverde AL. Atividade moluscicida de plantas: uma alternativa profilática. Rev Bras Farmacogn. 2010;20:282–6.

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