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Review
. 2014 Nov 15;59 Suppl 5(Suppl 5):S356-9.
doi: 10.1093/cid/ciu591.

Diagnosis and treatment of invasive fungal infections in the cancer patient: recent progress and ongoing questions

Affiliations
Review

Diagnosis and treatment of invasive fungal infections in the cancer patient: recent progress and ongoing questions

Dimitrios P Kontoyiannis et al. Clin Infect Dis. .

Abstract

In the last 5 years we have witnessed further developments in diagnosis and treatment of invasive fungal infections (IFIs) that complicate cancer chemotherapy. In this brief overview, we highlight some advancement, discuss future directions, and unmet needs in this complex area.

Keywords: Aspergillosis; cancer; candidiasis; diagnosis; treatment.

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References

    1. Patterson TF. Clinical utility and development of biomarkers in invasive aspergillosis. Trans Am Clin Climatol Assoc. 2010;122:174–83. - PMC - PubMed
    1. Mennink-Kersten MA, Donnelly JP, Verweij PE. Detection of circulating galactomannan for the diagnosis and management of invasive aspergillosis. Lancet Infect Dis. 2004;4:349–57. - PubMed
    1. Reinwald M, Hummel M, Kovalevskaya E, et al. Therapy with antifungals decreases the diagnostic performance of PCR for diagnosing invasive aspergillosis in bronchoalveolar lavage samples of patients with haematological malignancies. J Antimicrob Chemother. 2012;67:2260–7. - PubMed
    1. Fisher CE, Stevens AM, Leisenring W, Pergam SA, Boeckh M, Hohl TM. The serum galactomannan index predicts mortality in hematopoietic stem cell transplant recipients with invasive aspergillosis. Clin Infect Dis. 2013;57:1001–4. - PMC - PubMed
    1. Wiederhold NP, Najvar LK, Bocanegra R, Kirkpatrick WR, Patterson TF, Thornton CR. Interlaboratory and interstudy reproducibility of a novel lateral-flow device and influence of antifungal therapy on detection of invasive pulmonary aspergillosis. J Clin Microbiol. 2013;51:459–65. - PMC - PubMed

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