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Comment
. 2014 Oct 31;346(6209):542-3.
doi: 10.1126/science.1262123.

RNA. Complete pairing not needed

Affiliations
Comment

RNA. Complete pairing not needed

Dinshaw J Patel. Science. .

Abstract

Structures of microRNA-mRNA–human Argonaute reveal where and how intermolecular interactions are specified

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Figures

None
Superposition. The guide (g) RNA in binary (blue) (PDB: 4W5N) and ternary (purple) (PDB: 4W5O) complexes compares nucleotides 1, 5 to 7, and 13 to 16.
None

Comment on

  • Structural basis for microRNA targeting.
    Schirle NT, Sheu-Gruttadauria J, MacRae IJ. Schirle NT, et al. Science. 2014 Oct 31;346(6209):608-13. doi: 10.1126/science.1258040. Science. 2014. PMID: 25359968 Free PMC article.

References

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    1. Ha M, Kim VN. Nat. Rev. Mol. Cell Biol. 2014;15:509. - PubMed
    1. Schirle NT, et al. Science. 2014;346:608. - PMC - PubMed

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