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. 2014 Oct;30(5):241-4.
doi: 10.3393/ac.2014.30.5.241. Epub 2014 Oct 28.

Perianal Paget's Disease

Chang Woo Kim  1 , Yon Hee Kim  2 , Min Soo Cho  1 , Byung Soh Min  1 , Seung Hyuk Baik  1 , Nam Kyu Kim  1
Affiliations

Perianal Paget's Disease

Chang Woo Kim et al. Ann Coloproctol. 2014 Oct.

Abstract

The incidence of extramammary Paget's disease (EMPD) is very low. An 84-year-old Korean man was treated with topical and oral medications at a local dermatologic clinic for a year, but the symptoms did not improve. He visited Severance Hospital and underwent a perianal skin biopsy and was finally diagnosed with EMPD. The authors performed a wide local excision according to a 1-cm margin around the lesion. For the skin and the soft tissue defects, bilateral inferior gluteal artery perforator flap transpositions were performed. The size of the lesion was 14 cm(2) × 9 cm(2), and the lateral and the basal margins were all disease free.

Keywords: Extramammary Paget's disease; Perianal Paget's disease.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Position of the patient (A), after the wide local excision (B), the surgical specimen (C), and after the skin-flap transpositions (D).
Fig. 2
Fig. 2
Immunohistochemistry examinations: (A) H&E (×100), (B) cytokeratin 7 (×100), (C) carcinoembryonic antigen (×100), (D) C-erb B2 (×100), (E) HMB-45 (×100), and (F) mucicarmine (×100).
See this image and copyright information in PMC

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