Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Guideline
. 2014 Nov;12(11):1517-23.
doi: 10.6004/jnccn.2014.0151.

Central nervous system cancers, version 2.2014. Featured updates to the NCCN Guidelines

Louis Burt Nabors  1 , Jana Portnow  1 , Mario Ammirati  1 , Henry Brem  1 , Paul Brown  1 , Nicholas Butowski  1 , Marc C Chamberlain  1 , Lisa M DeAngelis  1 , Robert A Fenstermaker  1 , Allan Friedman  1 , Mark R Gilbert  1 , Jona Hattangadi-Gluth  1 , Deneen Hesser  1 , Matthias Holdhoff  1 , Larry Junck  1 , Ronald Lawson  1 , Jay S Loeffler  1 , Paul L Moots  1 , Maciej M Mrugala  1 , Herbert B Newton  1 , Jeffrey J Raizer  1 , Lawrence Recht  1 , Nicole Shonka  1 , Dennis C Shrieve  1 , Allen K Sills Jr  1 , Lode J Swinnen  1 , David Tran  1 , Nam Tran  1 , Frank D Vrionis  1 , Patrick Yung Wen  1 , Nicole R McMillian  1 , Maria Ho  1
Affiliations
Guideline

Central nervous system cancers, version 2.2014. Featured updates to the NCCN Guidelines

Louis Burt Nabors et al. J Natl Compr Canc Netw. 2014 Nov.

Abstract

The NCCN Guidelines for Central Nervous System Cancers provide multidisciplinary recommendations for the clinical management of patients with cancers of the central nervous system. These NCCN Guidelines Insights highlight recent updates regarding the management of metastatic brain tumors using radiation therapy. Use of stereotactic radiosurgery (SRS) is no longer limited to patients with 3 or fewer lesions, because data suggest that total disease burden, rather than number of lesions, is predictive of survival benefits associated with the technique. SRS is increasingly becoming an integral part of management of patients with controlled, low-volume brain metastases.

PubMed Disclaimer

References

    1. Barnholtz-Sloan JS, Sloan AE, Davis FG, et al. Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J Clin Oncol. 2004;22:2865–2872. - PubMed
    1. Schouten LJ, Rutten J, Huveneers HA, Twijnstra A. Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer. 2002;94:2698–2705. - PubMed
    1. Lin NU, Bellon JR, Winer EP. CNS metastases in breast cancer. J Clin Oncol. 2004;22:3608–3617. - PubMed
    1. Eichler AF, Loeffiler JS. Multidisciplinary management of brain metastases. Oncologist. 2007;12:884–898. - PubMed
    1. Suh JH. Stereotactic radiosurgery for the management of brain metastases. N Engl J Med. 2010;362:1119–1127. - PubMed

Publication types

MeSH terms