Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Sep 18;6(7 Spec No):13-7.
doi: 10.5539/gjhs.v6n7p13.

Association between helicobacter pylori infection and primary open angle glaucoma

V Samarai  1 , N Sharifi, Sh Nateghi
Affiliations

Association between helicobacter pylori infection and primary open angle glaucoma

V Samarai et al. Glob J Health Sci. .

Abstract

Aim: to compare the prevalence of Pylori infection in patients with primary open angle glaucoma (POAG) and control group with cataract.

Methods: This is a prospective case-control study. The participants were organized in two groups. First group (case) consisted of 35 patients with POAG and second group consisted of 35 age matched participants with cataract whose optic disk could be evaluated. Serum levels of anti H. pylori IgG antibody were evaluated with the method of ELISA.

Results: The seroprevalence of Pylori infection was 89.1 % (33 of 37) in patients with POAG and 59.5 % (25 of 42) in the control group. The difference was significant (P=0.008). The odds ratio for association between Pylori and POAG was 5.69 and the range of 95% confidence interval was from 1.58 to 20.50.

Conclusion: This study suggests that Helicobacter Pylori infection might be associated with primary open angle glaucoma.

PubMed Disclaimer

References

    1. Abdollahi A, Zarei R, Zare M, Kazemi A. Relationship between Helicobacter Pylori infection and primary open-angle glaucoma. Iran J Ophthalmol. 2005;18(2):15–19.
    1. Abrishami M, Kargozar A, Rashed T, Shoeibi N, Attaranzadeh A. Association of Helicobacter Pylori Infection with Primary Open Angle Glaucoma. Bina J Ophthalmol. 2007;12(3):289–293.
    1. Bron A, Chaine G, Villain M, et al. Risk factors for primary open-angle glaucoma. J Fr Ophtalmol. 2008;31(4):435–444. http://dx.doi.org/10.1016/S0181-5512(08)71443-8 . - PubMed
    1. Cantor L, Fechtner R. D, Michael A. J. Introduction to glaucoma, Basic and clinical science course: Glaucoma. San Francisco: Foundation of American Academy of Ophthalmology; 2004-2005. pp. 8–10.
    1. Cartwright M. J, Grajewski A. L, Anderson D. R, Friedberg M. L, Richards D. W. Immune-related disease and normal-tension glaucoma. A case-control study. Arch Ophthalmol. 1992;110(4):500–502. http://dx.doi.org/10.1001/archopht.1992.01080160078035 . - PubMed

Substances