Artefacts in histopathology
- PMID: 25364159
- PMCID: PMC4211218
- DOI: 10.4103/0973-029X.141346
Artefacts in histopathology
Abstract
Histopathology is the science of slide analysis for the diagnostic and research purposes. However, sometimes the presence of certain artefacts in a microscopic section can result in misinterpretations leading to diagnostic pitfalls that can result in increased patient morbidity. This article reviews the common artefacts encountered during slide examination alongside the remedial measures which can be undertaken to differentiate between an artefact and tissue constituent.
Keywords: Artefacts; diagnostic pitfalls; histopathology; morbidity; mortality; remedies.
Conflict of interest statement
Figures
References
-
- Margarone JE, Natiella JR, Vaughan CD. Artefacts in oral biopsy specimens. J Oral Maxillofac Surg. 1985;43:163–72. - PubMed
-
- Ficarra G, McClintock B, Hansen LS. Artefacts created during oral biopsy procedures. J Craniomaxillofac Surg. 1987;15:34–7. - PubMed
-
- Okun MR, Ellerin P, Piotrowicz MA. Prevention of ice crystal damage to biopsy specimens in transport. Arch Dermatol. 1972;105:458–9. - PubMed
-
- Kepes JJ, Oswald O. Tissue artefacts caused by sponge in embedded cassettes. Am J Surg Pathol. 1991;15:810–2. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources