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. 2014 Jan;35(1):103-7.
doi: 10.4103/0974-8520.141956.

Physico-Chemical profile of Puga Khanda: A Preliminary Study

Pramod C Baragi  1 , Umapati C Baragi  2 , Sathyanarayana Bhat  3 , Pradeep Kumar Prajapati  4
Affiliations

Physico-Chemical profile of Puga Khanda: A Preliminary Study

Pramod C Baragi et al. Ayu. 2014 Jan.

Abstract

Background: Herbal medicines are the oldest known form of medicine in the world. However, the quality control and the assurance still remains a challenge because of the high variability of chemical components. Herbal drugs, singlely or in combinations, contain numerous compounds in complex matrices in which no single active constituent is responsible for the overall efficacy. This creates a challenge in establishing quality control standards and the standardization of finished herbal products. Many formulations have been mentioned in Ayurvedic text for Vrushyatwa (aphrodisiac). Puga Khanda is one among such formulations.

Aim: To develop preliminary physico-chemical profile of Puga Khanda.

Materials and methods: Puga Khanda was prepared in three batches as per the classical reference mentioned in Bhaishajya Ratnavali. The formulation was subjected for physico-chemical analysis, phytochemical analysis and Thin Layer Chromatography (TLC).

Results and conclusion: The study revealed that organoleptic characters, pH and extractive values of all 3 samples were almost equal. All the samples had 60% of sugar needed for preservation and 2/3(rd) of it was non reducing sugar. The total alkaloids ranged from 0.002 to 0.004% w/w. In TLC study the entire samples showed similar pattern except the 2(nd) sample of Puga Khanda.

Keywords: Khanda Kalpana; Puga Khanda; pharmaceutical standardization; quality control.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Ashodhita Puga Phala
Figure 2
Figure 2
Shodhita Puga Phala
Figure 3
Figure 3
Puga Khanda
Figure 4
Figure 4
Thin Layer Chromatography of total alkaloidal fractions under long wave ultraviolet (366 nm). APC=Ashuddha Puga Churna; SPC=Shuddha Puga Churna; S1, Puga Khanda sample 1; S2=Puga Khanda sample 2; S3=Puga Khanda sample 3
Figure 5
Figure 5
Thin Layer Chromatography of total alkaloidal fractions under short wave ultraviolet (254 nm) APC= Ashuddha Puga Churna; SPC=Shuddha Puga Churna; S1=Puga Khanda sample 1; S2=Puga Khanda sample 2; S3=Puga Khanda sample 3
See this image and copyright information in PMC

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