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. 2015 Jan;59(1):721-3.
doi: 10.1128/AAC.04081-14. Epub 2014 Nov 3.

Chromosome-mediated multidrug resistance in Salmonella enterica serovar Typhi

Chien-Shun Chiou  1 , Munirul Alam  2 , Jung-Che Kuo  3 , Yen-Yi Liu  3 , Pei-Jen Wang  3
Affiliations

Chromosome-mediated multidrug resistance in Salmonella enterica serovar Typhi

Chien-Shun Chiou et al. Antimicrob Agents Chemother. 2015 Jan.

Abstract

A salmonella genomic island, designated SGI11, was found in 18 of 26 multidrug-resistant Salmonella enterica serovar Typhi isolates from Bangladesh. SGI11 was an IS1 composite transposon and carried 7 resistance genes that conferred resistance to 5 first-line antimicrobials. Eleven of the 18 SGI11-carrying S. Typhi isolates had developed resistance to high levels of ciprofloxacin.

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Figures

FIG 1
FIG 1
Schematic diagram of SGI11. A sequence-length scale, with values shown in bp, is indicated above the diagram of the ORFs, and the corresponding sequence positions and directions in plasmid pAKU_1 (GenBank accession number AM412236) are indicated at the top.
See this image and copyright information in PMC

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