Ufmylation of ASC1 is essential for breast cancer development

. 2014 Nov;4(11):OF10.

doi: 10.1158/2159-8290.CD-RW2014-201. Epub 2014 Sep 25.

No authors listed

No authors listed. Cancer Discov. 2014 Nov.

. 2014 Nov;4(11):OF10.

doi: 10.1158/2159-8290.CD-RW2014-201. Epub 2014 Sep 25.

Abstract

UFM1 modifies ASC1 to promote ERα transactivation and development of breast cancer.

Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development.
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Modification of ERα by UFM1 Increases Its Stability and Transactivity for Breast Cancer Development.
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Studies on the functional role of UFMylation in cells (Review).
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