doi: 10.1038/337525a0.
Designing CD4 immunoadhesins for AIDS therapy
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- PMID: 2536900
- DOI: 10.1038/337525a0
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Designing CD4 immunoadhesins for AIDS therapy
Nature.
.
Abstract
A newly-constructed antibody-like molecule containing the gp120-binding domain of the receptor for human immunodeficiency virus blocks HIV-1 infection of T cells and monocytes. Its long plasma half-life, other antibody-like properties, and potential to block all HIV isolates, make it a good candidate for therapeutic use.
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