Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Oct;6(4):384-6.
doi: 10.4103/0974-7796.141010.

Prostatic melanosis

Hasan Gucer  1 , Pelin Bagci  1
Affiliations
Case Reports

Prostatic melanosis

Hasan Gucer et al. Urol Ann. 2014 Oct.

Abstract

Prostatic melanosis is a very rare, benign lesion characterized by the presence of melanin in the epithelium of the prostate gland and stromal dendritic cells, requiring no additional treatment. It constitutes the melanocytic lesions of the prostate together with blue nevus and malignant melanoma. We present a case with prostatic melanosis because it is rarely seen and its distinction from malignant melanoma is clinicopathologically very important.

Keywords: Melanin; melanosis; prostate.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None.

Figures

Figure 1
Figure 1
Brown-black pigment in the dendritic stromal cells and glandular epithelial cells (H and E, ×40)
Figure 2
Figure 2
Brown-black pigment in the dendritic stromal cells and glandular epithelial cells (H and E, ×100)
Figure 3
Figure 3
Masson Fontana reaction highlights melanin (MF, ×200)
Figure 4
Figure 4
S-100 protein positivity in the stromal dendritic cells (S-100, ×400)
See this image and copyright information in PMC

References

    1. Paner GP, Aron M, Hansel DE, Amin MB. Non-epithelial neoplasms of the prostate. Histopathology. 2012;60:166–86. - PubMed
    1. Dailey VL, Hameed O. Blue nevus of the prostate. Arch Pathol Lab Med. 2011;135:799–802. - PubMed
    1. Klock C, Gomes R, João M, Netto G. Prostate melanosis associated with acinar adenocarcinoma. Int J Surg Pathol. 2010;18:379–80. - PubMed
    1. Furusato M, Matsumoto I, Kato H, Takahashi H, Kawashima Y, Wada T, et al. Prostatic carcinoma with melanosis. Prostate. 1989;15:65–9. - PubMed
    1. Anderco D, Lazăr E, Tăban S, Miclea F, Dema A. Prostatic blue nevus. Rom J Morphol Embryol. 2010;51:555–7. - PubMed

Publication types