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Review
. 2014 Oct;7(10):44-8.

Skin substitutes: an overview of the key players in wound management

Rajiv Nathoo  1 , Nicole Howe  2 , George Cohen  1
Affiliations
Review

Skin substitutes: an overview of the key players in wound management

Rajiv Nathoo et al. J Clin Aesthet Dermatol. 2014 Oct.

Abstract

In a relatively short timespan, a wealth of new skin substitutes made of synthetic and biologically derived materials have arisen for the purpose of wound healing of various etiologies. This review article focuses on providing an overview of skin substitutes including their indications, contraindications, benefits, and limitations. The result of this overview was an appreciation of the vast array of options available for clinicians, many of which did not exist a short time ago. Yet, despite the rapid expansion this field has undergone, no ideal skin substitute is currently available. More research in the field of skin substitutes and wound healing is required not only for the development of new products made of increasingly complex biomolecular material, but also to compare the existing skin substitutes.

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Figures

Figure 1
Figure 1
Skin substitutes; *UC = ulcerative colitischeeks
See this image and copyright information in PMC

References

    1. Neville JA, Housman TS, Letsinger JA, et al. Increase in procedures performed at dermatology office visits from 1995 to 2001. Dermatol Surg. 2005;31:160–162. - PubMed
    1. Singh A, Haider S, Menon GR, et al. Meta-analysis of randomized controlled trials on hydrocolloid occlusive dressing versus conventional gauze dressing in the healing of chronic wounds. Asian J Surg. 2004;27:326–332. - PubMed
    1. Franz MG, Steed DL, Robson MC. Optimizing healing of the acute wound by minimizing complications. Curr Probl Surg. 2007;44:691–763. - PubMed
    1. Zaulyanov L, Kirsner RS. A review of a bi-layered living cell treatment (Apligraf) in the treatment of venous leg ulcers and diabetic foot ulcers. Clin Interv Aging. 2007;2(1):93–98. - PMC - PubMed
    1. Del Rosso JQ. Wound care in the dermatology office: where are we in 2011. J Am Acad Dermatol. 2011;64(3 Suppl):S1–S7. - PubMed

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