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. 2015;44(3):927-35.
doi: 10.3233/JAD-142049.

Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes

Rebecca K West  1 , Ramit Ravona-Springer  2 , Anthony Heymann  3 , James Schmeidler  1 , Derek Leroith  4 , Keren Koifman  2 , Elizabeth Guerrero-Berroa  1 , Rachel Preiss  2 , Hadas Hoffman  2 , Jeremy M Silverman  5 , Michal Schnaider Beeri  6
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Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes

Rebecca K West et al. J Alzheimers Dis. 2015.

Abstract

We studied the relationship of adult body height with five cognitive outcomes (executive functioning, semantic categorization, attention/working memory, episodic memory, and an overall cognition measure) in 897 cognitively normal elderly with type 2 diabetes. Regression analyses controlling for sociodemographic, cardiovascular, and diabetes-related risk factors and depression demonstrated that in males, shorter stature was associated with poorer executive functioning (p = 0.001), attention/working memory (p = 0.007), and overall cognition (p = 0.016), but not with episodic memory (p = 0.715) or semantic categorization (p = 0.948). No relationship between height and cognition was found for females. In cognitively normal type 2 diabetes male subjects, shorter stature, a surrogate for early-life stress and poor nutrition, was associated with cognitive functions.

Keywords: Cognitive performance; height; risk factors; type 2 diabetes mellitus; vascular dementia.

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