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. 2012:2012:978479.
doi: 10.1155/2012/978479. Epub 2012 Oct 11.

Intrapleural bortezomib for the therapy of myelomatous pleural effusion: a case report

Magdalena Klanova  1 , Pavel Klener  1 , Marek Trneny  2 , Jan Straub  3 , Ivan Spicka  3
Affiliations

Intrapleural bortezomib for the therapy of myelomatous pleural effusion: a case report

Magdalena Klanova et al. Case Reports Immunol. 2012.

Abstract

Myelomatous pleural effusion (MPE) is an extremely rare manifestation of multiple myeloma (MM). We present a case of MPE in a patient with IgG-κ MM treated with intrapleural bortezomib with systemic bortezomib-based therapy. Although we observed good local response, the patient succumbed due to systemic myeloma progression.

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Figures

Figure 1
Figure 1
(a) Chest X-ray of patient showing massive left pleural effusion and (b) reduction of the pleural effusion after two doses of intrapleural bortezomib.
See this image and copyright information in PMC

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