Lrp5 regulation of bone mass and serotonin synthesis in the gut

Aruna Kode¹, Arnaud Obri², Riccardo Paone³, Stavroula Kousteni¹, Patricia Ducy⁴, Gerard Karsenty²

Affiliations

¹ Department of Physiology &Cellular Biophysics, College of Physicians &Surgeons, Columbia University, New York, New York, USA.
² Department of Genetics &Development, College of Physicians &Surgeons, Columbia University, New York, New York, USA.
³ Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
⁴ Department of Pathology &Cell Biology, College of Physicians &Surgeons, Columbia University, New York, New York, USA.

PMID: 25375916
DOI: 10.1038/nm.3698

Comment

Lrp5 regulation of bone mass and serotonin synthesis in the gut

Aruna Kode et al. Nat Med. 2014 Nov.

. 2014 Nov;20(11):1228-9.

doi: 10.1038/nm.3698.

Authors

Aruna Kode¹, Arnaud Obri², Riccardo Paone³, Stavroula Kousteni¹, Patricia Ducy⁴, Gerard Karsenty²

Affiliations

¹ Department of Physiology &Cellular Biophysics, College of Physicians &Surgeons, Columbia University, New York, New York, USA.
² Department of Genetics &Development, College of Physicians &Surgeons, Columbia University, New York, New York, USA.
³ Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
⁴ Department of Pathology &Cell Biology, College of Physicians &Surgeons, Columbia University, New York, New York, USA.

PMID: 25375916
DOI: 10.1038/nm.3698

No abstract available

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Comment in

Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
Cui Y, Niziolek PJ, MacDonald BT, Alenina N, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Powell DR, He X, Bader M, Williams BO, Warman ML, Robling AG. Cui Y, et al. Nat Med. 2014 Nov;20(11):1229-30. doi: 10.1038/nm.3697. Nat Med. 2014. PMID: 25375917 Free PMC article. No abstract available.

Comment on

Lrp5 functions in bone to regulate bone mass.
Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, Robinson DR, Zhong Z, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Liu Q, Mseeh F, Powell DR, Yang QM, Zambrowicz B, Gerrits H, Gossen JA, He X, Bader M, Williams BO, Warman ML, Robling AG. Cui Y, et al. Nat Med. 2011 Jun;17(6):684-91. doi: 10.1038/nm.2388. Epub 2011 May 22. Nat Med. 2011. PMID: 21602802 Free PMC article.

References

1. Nat Med. 2010 Mar;16(3):308-12 - PubMed
1. Nat Med. 2011 Jun;17(6):684-91 - PubMed
1. J Med Chem. 2014 Jun 12;57(11):4692-709 - PubMed
1. Cell. 2008 Nov 28;135(5):825-37 - PubMed
1. J Biol Chem. 2002 Sep 6;277(36):33275-83 - PubMed

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Lrp5 regulation of bone mass and serotonin synthesis in the gut

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