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. 2014 Oct 29:7:25543.
doi: 10.3402/gha.v7.25543. eCollection 2014.

Estimating cause of adult (15+ years) death using InterVA-4 in a rural district of southern Ghana

Elizabeth Awini  1 , Doris Sarpong  2 , Alexander Adjei  2 , Alfred Kwesi Manyeh  2 , Alberta Amu  2 , Patricia Akweongo  3 , Philip Adongo  3 , Vida Kukula  4 , Gabriel Odonkor  2 , Solomon Narh  2 , Margaret Gyapong  2
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Estimating cause of adult (15+ years) death using InterVA-4 in a rural district of southern Ghana

Elizabeth Awini et al. Glob Health Action. .

Abstract

Background: Data needed to estimate causes of death and the pattern of these deaths are scarce in sub-Saharan Africa. Such data are very important for targeting, monitoring, and evaluating health interventions.

Objective: To estimate the mortality rate and determine causes of death among adults (aged 15 years and older) in a rural district of southern Ghana, using the InterVA-4 model.

Design: Data used were generated from verbal autopsies conducted for registered adult members of the Dodowa Health and Demographic Surveillance System who died between 2006 and 2010. The InterVA-4 model was used to assign the cause of death.

Results: Overall, the mortality rate for the period under review was 7.5/1,000 person-years (py) for the general population and 10.4/1,000 py for those aged 15 and older. The leading cause of death was communicable diseases (CDs), with a malaria-specific mortality rate of 1.06/1,000 py. Pulmonary tuberculosis (TB)-specific mortality rate was the next highest (1.01/1,000 py). HIV/AIDS attributed deaths were lower among males than females. Non-communicable diseases (NCDs) contributed to 28.3% of the deaths with cause-specific mortality rate of 2.93/1,000 py. Stroke topped the list with cause-specific mortality rate of 0.69/1,000 py. As expected, young males (15-49 years) contributed to more road traffic accident (RTA) deaths; they had a lower RTA cause-specific mortality rate than older males (50-64 years).

Conclusions: Data indicate that CDs (e.g. malaria and TB) remain the major cause of death with NCDs (e.g. stroke) following closely behind. Verbal autopsy data can provide the causes of mortality in poorly resourced settings where access to timely and accurate data is scarce.

Keywords: Dodowa; Ghana; Health and Demographic Surveillance System; InterVA-4; adults; cause of death; verbal autopsy.

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Figures

Fig. 1
Fig. 1
Mortality rates per 1,000 person-years by cause group by sex (2006–2010).
Fig. 2
Fig. 2
Mortality rates per 1,000 person-years by cause group by year (2006–2010).
See this image and copyright information in PMC

References

    1. World Bank. World development indicators. In: Development Data Group, editor. World Bank free PDF; 2012. http://siteresources.worldbank.org/EXTANNREP2012/Resources/8784408-13462... [cited June 2013]
    1. Mathers CD, Ma Fat D, Inoue M, Rao C, Lopez AD. Counting the dead and what they died from: an assessment of the global status of cause of death data. Bull World Health Organ. 2005;83:171–177c. - PMC - PubMed
    1. Bryce J, Boschi-Pinto C, Shibuya K, Black RE. WHO estimates of the causes of death in children. Lancet. 2005;365:1147–52. - PubMed
    1. Morris SS, Black RE, Tomaskovic L. Predicting the distribution of under-five deaths by cause in countries without adequate vital registration systems. Int J Epidemiol. 2003;32:1041–51. - PubMed
    1. Lozano R, Freeman MK, James SL, Campbell B, Lopez AD, Flaxman AD, et al. Performance of InterVA for assigning causes of death to verbal autopsies: multisite validation study using clinical diagnostic gold standards. Popul Health Metr. 2011;9:50. - PMC - PubMed

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