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Comment
. 2014 Nov;19(11):1207.
doi: 10.1634/theoncologist.2014-0267.

Giant cell tumor of bone

Luigi Cavanna  1 , Claudia Biasini  1 , Michela Monfredo  1 , Pietro Maniscalco  2 , Monica Mori  3
Affiliations
Comment

Giant cell tumor of bone

Luigi Cavanna et al. Oncologist. 2014 Nov.

Abstract

The role of enhanced fluorodeoxyglucose F 18 uptake of giant cell tumor of bone (GCTB) should be mentioned in an overview such as that reported by van der Heijden et al., with regard not only to the response to denosumab treatment for unresectable GCTB but also to the clinical implications for the diagnosis of this disease.

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Figures

Figure 1.
Figure 1.
Positron emission tomography/computed tomography showing enhanced F-18 fluorodeoxy-D-glucose uptake at the level of the proximal end of the right fibula.
See this image and copyright information in PMC

Comment in

  • In reply.
    van der Heijden L, Dijkstra PD, van de Sande MA, Kroep JR, Nout RA, van Rijswijk CS, Bovée JV, Hogendoorn PC, Gelderblom H. van der Heijden L, et al. Oncologist. 2014 Nov;19(11):1208. doi: 10.1634/theoncologist.2014-0332. Oncologist. 2014. PMID: 25378542 Free PMC article.

Comment on

  • The clinical approach toward giant cell tumor of bone.
    van der Heijden L, Dijkstra PD, van de Sande MA, Kroep JR, Nout RA, van Rijswijk CS, Bovée JV, Hogendoorn PC, Gelderblom H. van der Heijden L, et al. Oncologist. 2014 May;19(5):550-61. doi: 10.1634/theoncologist.2013-0432. Epub 2014 Apr 9. Oncologist. 2014. PMID: 24718514 Free PMC article. Review.

References

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    1. Thomas D, Henshaw R, Skubitz K, et al. Denosumab in patients with giant-cell tumour of bone: An open-label, phase 2 study. Lancet Oncol. 2010;11:275–280. - PubMed
    1. Shin D-S, Shon O-J, Han D-S, et al. The clinical efficacy of (18)F-FDG-PET/CT in benign and malignant musculoskeletal tumors. Ann Nucl Med. 2008;22:603–609. - PubMed
    1. Thomas DM, Skubitz KM. Giant cell tumour of bone. Curr Opin Oncol. 2009;21:338–344. - PubMed
    1. Tubbs WS, Brown LR, Beabout JW, et al. Benign giant-cell tumor of bone with pulmonary metastases: Clinical findings and radiologic appearance of metastases in 13 cases. AJR Am J Roentgenol. 1992;158:331–334. - PubMed

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