Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Nov;19(11):1208.
doi: 10.1634/theoncologist.2014-0332.

In reply

Affiliations
Comment

In reply

Lizz van der Heijden et al. Oncologist. 2014 Nov.

Abstract

The authors respond to the observations and remarks of Cavanna et al. concerning the clinical guidance paper on giant cell tumor of bone (GCTB) in the era of denosumab and update the paper with respect to the European Medicines Agency’s recent positive opinion recommending denosumab for the treatment of adults and skeletally mature adolescents with GCTB that is unresectable or for which surgical resection is likely to result in severe morbidity

PubMed Disclaimer

Comment on

  • The clinical approach toward giant cell tumor of bone.
    van der Heijden L, Dijkstra PD, van de Sande MA, Kroep JR, Nout RA, van Rijswijk CS, Bovée JV, Hogendoorn PC, Gelderblom H. van der Heijden L, et al. Oncologist. 2014 May;19(5):550-61. doi: 10.1634/theoncologist.2013-0432. Epub 2014 Apr 9. Oncologist. 2014. PMID: 24718514 Free PMC article. Review.
  • Giant cell tumor of bone.
    Cavanna L, Biasini C, Monfredo M, Maniscalco P, Mori M. Cavanna L, et al. Oncologist. 2014 Nov;19(11):1207. doi: 10.1634/theoncologist.2014-0267. Oncologist. 2014. PMID: 25378541 Free PMC article.

References

    1. Cavanna L, Biasini C, Monfredo M, et al. Giant cell tumor of bone. The Oncologist. 2014 (in press) - PMC - PubMed
    1. van der Heijden L, Dijkstra PDS, van de Sande MAJ, et al. The clinical approach toward giant cell tumor of bone. The Oncologist. 2014;19:550–561. - PMC - PubMed
    1. Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 21-24 July 2014. Available at http://www.ema.europa.eu/ema/index.jsp?curl=pages/news_and_events/news/2.... Accessed August 20, 2014.
    1. van der Bijl AE, Taminiau AH, Hermans J, et al. Accuracy of the Jamshidi trocar biopsy in the diagnosis of bone tumors. Clin Orthop Relat Res. 1997:233–243. - PubMed
    1. ESMO/European Sarcoma Network Working Group Bone sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2012;23(suppl 7):vii100–vii109. - PubMed