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Case Reports
. 2014 Sep 30;3(9):2047981614530286.
doi: 10.1177/2047981614530286. eCollection 2014 Oct.

Congenital thyroid hemiagenesis with multinodular goiter

Sk Bhartiya  1 , A Verma  2 , S Basu  1 , Vk Shukla  1
Affiliations
Case Reports

Congenital thyroid hemiagenesis with multinodular goiter

Sk Bhartiya et al. Acta Radiol Short Rep. .

Abstract

Thyroid hemiagenesis is a rare form of thyroid dysgenesis characterized by an absence of half of the thyroid gland. Developmental hemi-thyroid anomalies can result from either an abnormal descent or an agenesis of one lobe of the thyroid gland. We report a case of a 40-year-old woman with history of a longstanding gradually progressive thyroid swelling without any complication. An ultrasonographic examination diagnosed the absence of the left thyroid lobe and enlargement of the right lobe, which was confirmed on a computed tomography (CT) angiogram and a radionuclide scan of the neck. A cytological examination showed nodular goiter with cystic degeneration. Right subtotal thyroidectomy was performed and histopathological examination confirmed adenomatous goiter with degenerative changes. We report the rarity of the condition and emphasize the role of a comprehensive radiological, cytological, and radionuclide algorithm for an accurate preoperative diagnosis and subsequent management.

Keywords: CT angiography; Head and neck; radionuclide studies; thyroid.

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Figures

Fig. 1.
Fig. 1.
High frequency ultrasonography revealed empty left thyroid fossa.
Fig. 2.
Fig. 2.
(a) Oblique coronal (35°) thick MIP reconstruction of CT angiogram, showing major neck vessels and their branches. On the right side, the thyrocervical trunk shows origin of inferior thyroid artery (straight arrow) ascending upwards. On the left side, no comparable ascending branch could be noted from the thyrocervical trunk (hollow arrow), which was dividing to end as intercostals and muscular arteries. (b) Axial oblique (20°) thick MIP reconstruction of helical non-contrast CT scan neck, showing an empty left thyroid fossa (hollow arrow). Note the normal hyper-attenuating thyroid tissue in the right thyroid fossa (straight arrow).
Fig. 3.
Fig. 3.
Thyroid scintigraphy revealed absence of left lobe with isthmus.
See this image and copyright information in PMC

References

    1. Tiwari PK, Baxi M, Baxi J, et al. Right-sided hemiagenesis of the thyroid lobe and isthmus: A case report. Indian J Radiol Imaging 2008; 18: 313–315. - PMC - PubMed
    1. Maiorana R, Carta A, Floriddia G, et al. Thyroid hemiagenesis: prevalence in normal children and effect on thyroid function. J Clin Endocrinol Metab 2003; 88: 1534–1536. - PubMed
    1. Shabana W, Delange F, Freson M, et al. Prevalence of thyroid hemiagenesis: ultrasound screening in normal children. Eur J Pediatr 2000; 159: 496–498. - PubMed
    1. McHenry CR, Walfish PG, Rosen IB, et al. Congenital thyroid hemiagenesis. Am Surg 1995; 61: 634–639. - PubMed
    1. Mikosch P, Gallowitsch HJ, Kresnik E, et al. Thyroid hemiagenesis in an endemic goiter area diagnosed by ultrasonography: report of sixteen patients. Thyroid 1999; 9: 1075–1084. - PubMed

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