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. 2014 Aug 11:6:10-3.
doi: 10.1016/j.mmcr.2014.08.003. eCollection 2014 Oct.

Central nervous system cryptococcoma in a Ugandan patient with Human Immunodeficiency Virus

Sruti S Velamakanni  1 , Nathan C Bahr  2 , Abdu K Musubire  3 , David R Boulware  4 , Joshua Rhein  2 , Henry W Nabeta  3
Affiliations

Central nervous system cryptococcoma in a Ugandan patient with Human Immunodeficiency Virus

Sruti S Velamakanni et al. Med Mycol Case Rep. .

Abstract

Mortality due to AIDS-related Cryptococcal meningitis (CM) is often >50% in low-middle income countries. Dissemination of CM can result in intracranial mass lesions known as cryptococcoma. Patients who develop cryptococcomas often have worse outcomes when compared to patients with cryptococcosis without cryptococcoma. We describe a cryptococcoma in the central nervous system (CNS) in a Ugandan patient with AIDS, and review the diagnosis and management with special focus on difficulties encountered in low or middle-income countries.

Keywords: Central nervous system; Cryptococcoma; Cryptococcus meningitis; Human Immunodeficiency Virus; Immunosuppressed Host.

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Figures

Fig. 1
Fig. 1
Brain CT images showing evolution of cryptococcoma. 1a (left) The patient׳s CT image from October 2013, and 1b (right) the patient׳s CT image from December 2013.
See this image and copyright information in PMC

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