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. 1989:23 Suppl:S87-9.
doi: 10.1007/BF00647248.

Multimodal treatment of hepatocellular carcinoma

Y Shimamura  1 , Y Takenaka, M Ishii, Y Shima, H Taniguchi, Y Kitai, H Watanabe, S Sugai, A Takashi, T Kitaya, et al.
Affiliations

Multimodal treatment of hepatocellular carcinoma

Y Shimamura et al. Cancer Chemother Pharmacol. 1989.

Abstract

Our multimodal treatment of hepatocellular carcinoma (HCC) has brought about a significant improvement of the survival rate. It consists of a combination of hepatectomy and transcatheter arterial embolization using lipiodol (L-TAE). In order to facilitate L-TAE, we have developed a special catheter with notches. A group of patients with HCC (124 cases), excluding cases with absolutely non-curative resections and operative deaths, were treated between December 1980 and November 1986. Each case was treated for more than 1 year after hepatectomy. The patients were divided into two groups: A, patients with a single tumor not larger than 5 cm, and B, cases with larger tumors or more than one lesion. Some patients in each group were treated with L-TAE after hepatectomy. In group A, there was no significant difference in survival between treated and non-treated cases. In group B, L-TAE gave a significantly better survival than no postoperative treatment.

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