Discovery heralds new approach to the treatment of cystic fibrosis
- PMID: 25384240
- DOI: 10.1021/jm5016928
Discovery heralds new approach to the treatment of cystic fibrosis
Comment on
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Discovery of N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (VX-770, ivacaftor), a potent and orally bioavailable CFTR potentiator.J Med Chem. 2014 Dec 11;57(23):9776-95. doi: 10.1021/jm5012808. Epub 2014 Dec 2. J Med Chem. 2014. PMID: 25441013
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