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Review
. 2014:2014:748654.
doi: 10.1155/2014/748654. Epub 2014 Oct 15.

Prevalence of and risk factors for dry eye symptom in mainland china: a systematic review and meta-analysis

Ning-Ning Liu  1 , Lei Liu  1 , Jun Li  2 , Yi-Zhou Sun  1
Affiliations
Review

Prevalence of and risk factors for dry eye symptom in mainland china: a systematic review and meta-analysis

Ning-Ning Liu et al. J Ophthalmol. 2014.

Abstract

Purpose. To evaluate the pooled prevalence rate and risk factors of dry eye symptoms (DES) in mainland China. Methods. All the published population-based studies investigating the prevalence of DES in China were searched and evaluated against inclusion criteria. A systematic review and meta-analysis were performed. Results. Twelve out of the 119 identified studies were included in the meta-analysis. The pooled prevalence of DES in China was 17.0%. Female individuals, subjects living in the Northern and Western China, and over 60 years of age had significantly higher prevalent rates (21.6%, 17.9%, 31.3%, and 34.4%, resp.) compared with their counterparts. Patients with diabetes were also found to be more vulnerable to DES. Conclusions. The pooled prevalence rate of DES in mainland China was lower than that in other Asian regions and countries. A remarkable discrepancy in the prevalence in different geographic regions was noted. Aging, female gender, and diabetes were found to be risk factors for DES in China.

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Figures

Figure 1
Figure 1
Flow chart demonstrating how the identified published studies were included in the meta-analysis.
Figure 2
Figure 2
(a) A forest plot displaying the pooled prevalence of dry eye syndromes (DES) in the population of mainland China. (b) A funnel plot of studies conducted on the prevalence of DES in China. (c) A forest plot displaying the pooled prevalence of DES in the male gender in China. (d) A forest plot displaying the pooled prevalence of DES in the female gender in China.
Figure 3
Figure 3
(a) A forest plot displaying the pooled prevalence of DES in individuals living in Northern China. (b) A forest plot displaying the pooled prevalence of DES in individuals living in Southern China. (c) A forest plot displaying the pooled prevalence of DES in individuals living in urban China. (d) A forest plot displaying the pooled prevalence of DES in individuals living in rural China.
Figure 4
Figure 4
A map displaying the prevalence rates and geographic locations in China from 12 studies included in the meta-analysis.
See this image and copyright information in PMC

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