Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Sep;8(9):HC19-22.
doi: 10.7860/JCDR/2014/9567.4890. Epub 2014 Sep 20.

Anti hypertensive prescribing patterns and cost analysis for primary hypertension: a retrospective study

Rachana Pr  1 , Anuradha Hv  2 , Mc Shivamurthy  3
Affiliations

Anti hypertensive prescribing patterns and cost analysis for primary hypertension: a retrospective study

Rachana Pr et al. J Clin Diagn Res. 2014 Sep.

Abstract

Objective: The present study was conducted to analyze the current prescription pattern and cost analysis of antihypertensive drugs in hypertensive patients in a tertiary care hospital.

Materials and methods: A retrospective cross-sectional study was conducted in tertiary care hospital, Bangalore for three months and utilized 300 prescriptions for the analysis. The data analysed from the prescription included patients demographics, stage of hypertension according to JNC VII guidelines, type of drug therapy, class of anti-hypertensive, and cost effectiveness of therapy. Drug acquisition costs was calculated, using the cost of the cheapest available drug and the most commonly prescribed dosage, for each drug on a daily and annual basis. Total annual drug expenditure on buying required doses of all antihypertensive prescribed in the study population for a year was calculated.

Results: Monotherapy (48.94%) was leading trends of antihypertensive therapy followed by fixed dose combination (35.04%) and polytherapy (16.01%). The most frequent antihypertensive class to be prescribed were CCBs (38.59%) followed by beta blockers (24.07%). The ranking in terms of cost utilized per year from the highest to the lowest found in this study was: alpha blockers> ACE-inhibitors> ARBs> CCBs> beta blockers > diuretics. The diuretics were most cost-effective (Cost per day: 5.89 ± 2.87; Cost per year: 2129.02 ± 1080.49) in relation to the other antihypertensive prescribed.

Keywords: Antihypertensive drugs; Cost analysis; Hypertension; Prescription-pattern.

PubMed Disclaimer

Figures

[Table/Fig-2]:
[Table/Fig-2]:
Percentage of antihypertensive medication as monotherapy
[Table/Fig-3]:
[Table/Fig-3]:
Percentage of antihypertensive medication as FDC
[Table/Fig-4]:
[Table/Fig-4]:
Percentage of antihypertensive medication as polytherapy
See this image and copyright information in PMC

References

    1. PM Kearney, M Whelton, K Reynolds, P Muntner, PK Whelton, J He. Global burden of hypertension: analysis of worldwide data. Lancet. 2005;365:217–23. - PubMed
    1. RB Singh, IL Suh, VP Singh, S Chaithiraphan, P Laothavorn, SY RG, et al. Hypertension and stroke in Asia: Prevalence, control and strategies in developing countries for prevention. J Hum Hypertens. 2000;14:749–63. - PubMed
    1. PR Kokiwar, SS Gupta, PM Durge. Prevalence of hypertension in a rural community of central India. J Assoc Physicians India. 2012;60:26–29. - PubMed
    1. SS Lim, T Vos, AD Flaxman, G Danaei, K Shibuya, H Adair- Rohani, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2013;380:2224–60. - PMC - PubMed
    1. V Patel, S Chatterji, D Chisholm, S Ebrahim, G Gopalakrishna, C Mathers, et al. Chronic diseases and injuries in India. Lancet. 2011;377:413–28. - PubMed

LinkOut - more resources