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. 1989 Jan;9(1):321-4.
doi: 10.1128/mcb.9.1.321-324.1989.

An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene

S E Hyman  1 , M Comb, J Pearlberg, H M Goodman
Affiliations

An AP-2 element acts synergistically with the cyclic AMP- and phorbol ester-inducible enhancer of the human proenkephalin gene

S E Hyman et al. Mol Cell Biol. 1989 Jan.

Abstract

An enhancer with two DNA elements, one containing the sequence CGTCA, is required for cyclic AMP- and phorbol ester-inducible transcription of the human proenkephalin gene. We report that an AP-2 element located adjacent to the enhancer acts synergistically with it to confer maximal response to cyclic AMP and phorbol esters.

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References

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