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Review
. 2015 Jan;88(1045):20140634.
doi: 10.1259/bjr.20140634.

Small animal image-guided radiotherapy: status, considerations and potential for translational impact

K T Butterworth  1 , K M Prise, F Verhaegen
Affiliations
Review

Small animal image-guided radiotherapy: status, considerations and potential for translational impact

K T Butterworth et al. Br J Radiol. 2015 Jan.

Abstract

Radiation biology is being transformed by the implementation of small animal image-guided precision radiotherapy into pre-clinical research programmes worldwide. We report on the current status and developments of the small animal radiotherapy field, suggest criteria for the design and execution of effective studies and contend that this powerful emerging technology, used in combination with relevant small animal models, holds much promise for translational impact in radiation oncology.

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References

    1. Verhaegen F, Granton P, Tryggestad E. Small animal radiotherapy research platforms. Phys Med Biol 2011; 56: R55–83. doi: 10.1088/0031-9155/56/12/R01 - DOI - PubMed
    1. University of British Columbia. Available from: http://www.ubc.ca/
    1. Van Hoof SJ, Granton PV, Verhaegen F. Development and validation of a treatment planning system for small animal radiotherapy: SmART-Plan. Radiother Oncol 2013; 109: 361–6. doi: 10.1016/j.radonc.2013.10.003 - DOI - PubMed
    1. Verhaegen F, van Hoof S, Granton PV, Trani D. A review of treatment planning for precision image-guided photon beam pre-clinical animal radiation studies. Z Med Phys Mar 2014. Epub ahead of print. doi: 10.1016/j.zemedi.2014.02.004 - DOI - PubMed
    1. Granton PV, Podesta M, Landry G, Nijsten S, Bootsma G, Verhaegen F. A combined dose calculation and verification method for a small animal precision irradiator based on onboard imaging. Med Phys 2012; 39: 4155–66. doi: 10.1118/1.4725710 - DOI - PubMed

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