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. 1989 Jan 16;477(1-2):400-3.
doi: 10.1016/0006-8993(89)91436-4.

Autoradiographic study of mu and delta opioid binding sites and neutral endopeptidase-24.11 in rat after dorsal root rhizotomy

J M Zajac  1 , M C Lombard, M Peschanski, J M Besson, B P Roques
Affiliations

Autoradiographic study of mu and delta opioid binding sites and neutral endopeptidase-24.11 in rat after dorsal root rhizotomy

J M Zajac et al. Brain Res. .

Abstract

Highly selective tritiated ligands and autoradiography have been used to study mu and delta binding sites as well as neutral endopeptidase-24.11 in the dorsal horn of the rat spinal cord. Two weeks and 4 months after dorsal root rhizotomy, both opioid binding sites were dramatically decreased (congruent to 60%). In contrast, the level of neutral endopeptidase-24.11 remained unaltered.

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