Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2015 May;26(5):1001-3.
doi: 10.1681/ASN.2014090952. Epub 2014 Nov 13.

We don't prescribe statins to lower cholesterol: we prescribe statins to reduce vascular risk

Marcello Tonelli  1
Affiliations
Editorial

We don't prescribe statins to lower cholesterol: we prescribe statins to reduce vascular risk

Marcello Tonelli. J Am Soc Nephrol. 2015 May.
No abstract available

Keywords: ABC transporter; ACE inhibitors; access blood flow; access flow rate; acidosis; acute allograft rejection.

PubMed Disclaimer

Comment on

  • Contrasting Cholesterol Management Guidelines for Adults with CKD.
    Colantonio LD, Baber U, Banach M, Tanner RM, Warnock DG, Gutiérrez OM, Safford MM, Wanner C, Howard G, Muntner P. Colantonio LD, et al. J Am Soc Nephrol. 2015 May;26(5):1173-80. doi: 10.1681/ASN.2014040400. Epub 2014 Nov 13. J Am Soc Nephrol. 2015. PMID: 25395432 Free PMC article.

References

    1. Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, Bhala N, Peto R, Barnes EH, Keech A, Simes J, Collins R; Cholesterol Treatment Trialists’ (CTT) Collaboration: Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 376: 1670–1681, 2010 - PMC - PubMed
    1. Tonelli M, Muntner P, Lloyd A, Manns B, Klarenbach S, Pannu N, James M, Hemmelgarn B; Alberta Kidney Disease Network: Association between LDL-C and risk of myocardial infarction in CKD. J Am Soc Nephrol 24: 979–986, 2013 - PMC - PubMed
    1. Tonelli M, Muntner P, Lloyd A, Manns BJ, Klarenbach S, Pannu N, James MT, Hemmelgarn BR; Alberta Kidney Disease Network: Risk of coronary events in people with chronic kidney disease compared with those with diabetes: A population-level cohort study. Lancet 380: 807–814, 2012 - PubMed
    1. Tonelli M, Wanner C; Kidney Disease: Improving Global Outcomes Lipid Guideline Development Work Group Members: Lipid management in chronic kidney disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2013 clinical practice guideline. Ann Intern Med 160: 182, 2014 - PubMed
    1. Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH, Goldberg AC, Gordon D, Levy D, Lloyd-Jones DM, McBride P, Schwartz JS, Shero ST, Smith SC, Jr, Watson K, Wilson PW, Eddleman KM, Jarrett NM, LaBresh K, Nevo L, Wnek J, Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, DeMets D, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen WK, Smith SC, Jr, Tomaselli GF; American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129[Suppl 2]: S1–S45, 2014 - PubMed

Substances