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Review
. 2014 Oct 30:13:11.
doi: 10.4103/1477-3163.143720. eCollection 2014.

Esophageal cancer: Recent advances in screening, targeted therapy, and management

Affiliations
Review

Esophageal cancer: Recent advances in screening, targeted therapy, and management

Puja Gaur et al. J Carcinog. .

Abstract

The incidence of esophageal cancer remains on the rise worldwide and despite aggressive research in the field of gastrointestinal oncology, the survival remains poor. Much remains to be defined in esophageal cancer, including the development of an effective screening tool, identifying a good tumor marker for surveillance purposes, ways to target esophageal cancer stem cells as well as circulating tumor cells, and developing minimally invasive protocols to treat early-stage disease. The goal of this chapter is to highlight some of the recent advances and ongoing research in the field of esophageal cancer.

Keywords: Barrett's; cancer stem cells; carcinogenesis/tumorigenesis; dysplasia; esophageal cancer; targeted therapy.

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Conflict of interest statement

Conflict of Interest: None declared.

References

    1. American Cancer Society. Cancer Facts and Figures 2014. Atlanta GACS. 2014. [Last accessed on 2014 Aug 02]. Available from: http://www.cancer.org/acs/groups/content/@research/documents/webcontent/... .
    1. Siegel R, Naishadham D, Jemal A. Cancer statistics for Hispanics/Latinos, 2012. CA Cancer J Clin. 2012;62:283–98. - PubMed
    1. Chandra S, Gorospe EC, Leggett CL, Wang KK. Barrett's esophagus in 2012: Updates in pathogenesis, treatment, and surveillance. Curr Gastroenterol Rep. 2013;15:322. - PMC - PubMed
    1. Peters FP, Curvers WL, Rosmolen WD, de Vries CE, Ten Kate FJ, Krishnadath KK, et al. Surveillance history of endoscopically treated patients with early Barrett's neoplasia: Nonadherence to the Seattle biopsy protocol leads to sampling error. Dis Esophagus. 2008;21:475–9. - PubMed
    1. Corley DA, Mehtani K, Quesenberry C, Zhao W, de Boer J, Weiss NS. Impact of endoscopic surveillance on mortality from Barrett's esophagus-associated esophageal adenocarcinomas. Gastroenterology. 2013;145:312–9e1. - PMC - PubMed