Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Oct;93(17):267-279.
doi: 10.1097/MD.0000000000000089.

Hepatosplenic cat scratch disease in immunocompetent adults: report of 3 cases and review of the literature

Affiliations
Review

Hepatosplenic cat scratch disease in immunocompetent adults: report of 3 cases and review of the literature

Juan C García et al. Medicine (Baltimore). 2014 Oct.

Erratum in

Abstract

Cat-scratch disease (CSD) is the most frequent presentation of Bartonella henselae infection. It has a worldwide distribution and is associated with a previous history of scratch or bite from a cat or dog. CSD affects children and teenagers more often (80%) than adults, and it usually has a self-limiting clinical course. Atypical clinical course or systemic symptoms are described in 5%-20% of patients. Among them, hepatosplenic (HS) forms (abscess) have been described. The majority of published cases have affected children or immunosuppressed patients. Few cases of HS forms of CSD in immunocompetent adult hosts have been reported, and data about the management of this condition are scarce. Herein, we present 3 new cases of HS forms of CSD in immunocompetent adults and review 33 other cases retrieved from the literature. We propose an approach to clinical diagnosis and treatment with oral azithromycin.

PubMed Disclaimer

Conflict of interest statement

Financial support and conflicts of interest: The authors have no funding or conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Solitary liver hypodense lesion with target aspect (arrow) of Case 1.
FIGURE 2
FIGURE 2
Solitary spleen hypodense lesion (arrow) of Case 1.
FIGURE 3
FIGURE 3
Multiple hypodense liver lesions of Case 2.
FIGURE 4
FIGURE 4
Multiple hypodense liver lesions of Case 2.
FIGURE 5
FIGURE 5
Multiple hypodense spleen lesions of Case 3.

References

    1. Anderson BE, Neuman MA. Bartonella spp. as emerging human pathogens. Clin Microbiol Rev. 1997;10:203–219. - PMC - PubMed
    1. Angelakis E, Edouard S, La Scola B, et al. Bartonella henselae in skin biopsy specimens of patients with cat-scratch disease. Emerg Infect Dis. 2010;16:1963–1965. - PMC - PubMed
    1. Angelakis E, Roux V, Raoult D, et al. Real-time PCR strategy and detection of bacterial agents of lymphadenitis. Eur J Clin Microbiol Infect Dis. 2009;28:1363–1368. - PubMed
    1. Anyfantakis D, Kastanakis M, Papadomichelakis A, et al. Cat-scratch disease presenting as a solitary splenic abscess in an immunocompetent adult: case report and literature review. Infez Med. 2013;2:130–133. - PubMed
    1. Arisoy ES, Correa AG, Wagner ML, et al. Hepatosplenic cat-scratch disease in children: Selected clinical features and treatment. Clin Infect Dis. 1998;28:778–784. - PubMed