Parkinson's disease in GTP cyclohydrolase 1 mutation carriers
- PMID: 25398233
- PMCID: PMC5963397
- DOI: 10.1093/brain/awu308
Parkinson's disease in GTP cyclohydrolase 1 mutation carriers
Comment in
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Reply: Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.Brain. 2015 May;138(Pt 5):e352. doi: 10.1093/brain/awu309. Epub 2014 Nov 14. Brain. 2015. PMID: 25398234 Free PMC article. No abstract available.
Comment on
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Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.Brain. 2014 Sep;137(Pt 9):2480-92. doi: 10.1093/brain/awu179. Epub 2014 Jul 2. Brain. 2014. PMID: 24993959 Free PMC article.
References
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- Antoniades C, Cunnington C, Antonopoulos A, Neville M, Margaritis M, Demosthenous M, et al. Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis. Circulation. 2011;124:1860–70. - PMC - PubMed
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- Crabtree MJ, Tatham AL, Al-Wakeel Y, Warrick N, Hale AB, Cai S, et al. Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression. J Biol Chem. 2009a;284:1136–44. - PubMed
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- Crabtree MJ, Tatham AL, Hale AB, Alp NJ, Channon KM. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways. J Biol Chem. 2009b;284:28128–36. - PMC - PubMed
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