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Comment
. 2015 May;138(Pt 5):e352.
doi: 10.1093/brain/awu309. Epub 2014 Nov 14.

Reply: Parkinson's disease in GTP cyclohydrolase 1 mutation carriers

Niccolo E Mencacci  1 , Alan M Pittman  2 , Ioannis U Isaias  3 , John Hardy  2 , Stephan Klebe  4 , Kailash P Bhatia  5 , Nicholas W Wood  6
Affiliations
Comment

Reply: Parkinson's disease in GTP cyclohydrolase 1 mutation carriers

Niccolo E Mencacci et al. Brain. 2015 May.
No abstract available

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Comment on

  • Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
    Mencacci NE, Isaias IU, Reich MM, Ganos C, Plagnol V, Polke JM, Bras J, Hersheson J, Stamelou M, Pittman AM, Noyce AJ, Mok KY, Opladen T, Kunstmann E, Hodecker S, Münchau A, Volkmann J, Samnick S, Sidle K, Nanji T, Sweeney MG, Houlden H, Batla A, Zecchinelli AL, Pezzoli G, Marotta G, Lees A, Alegria P, Krack P, Cormier-Dequaire F, Lesage S, Brice A, Heutink P, Gasser T, Lubbe SJ, Morris HR, Taba P, Koks S, Majounie E, Raphael Gibbs J, Singleton A, Hardy J, Klebe S, Bhatia KP, Wood NW; International Parkinson’s Disease Genomics Consortium and UCL-exomes consortium. Mencacci NE, et al. Brain. 2014 Sep;137(Pt 9):2480-92. doi: 10.1093/brain/awu179. Epub 2014 Jul 2. Brain. 2014. PMID: 24993959 Free PMC article.
  • Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
    Ryan BJ, Crabtree MJ, Channon KM, Wade-Martins R. Ryan BJ, et al. Brain. 2015 May;138(Pt 5):e348. doi: 10.1093/brain/awu308. Epub 2014 Nov 14. Brain. 2015. PMID: 25398233 Free PMC article. No abstract available.
  • Parkinsonism in GTP cyclohydrolase 1-deficient DOPA-responsive dystonia.
    Furukawa Y, Kish SJ. Furukawa Y, et al. Brain. 2015 May;138(Pt 5):e351. doi: 10.1093/brain/awu325. Epub 2014 Nov 21. Brain. 2015. PMID: 25416181 Free PMC article. No abstract available.
  • Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.
    Terbeek J, Hermans S, Van Laere K, Vandenberghe W. Terbeek J, et al. Brain. 2015 May;138(Pt 5):e350. doi: 10.1093/brain/awu324. Epub 2014 Nov 28. Brain. 2015. PMID: 25433916 Free PMC article. No abstract available.
  • Parkinsonism in GTP cyclohydrolase 1 mutation carriers.
    Guella I, Sherman HE, Appel-Cresswell S, Rajput A, Rajput AH, Farrer MJ. Guella I, et al. Brain. 2015 May;138(Pt 5):e349. doi: 10.1093/brain/awu341. Epub 2014 Dec 13. Brain. 2015. PMID: 25497597 Free PMC article. No abstract available.

References

    1. Antoniades C, Cunnington C, Antonopoulos A, Neville M, Margaritis M, Demosthenous M, et al. Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis. Circulation. 2011;124:1860–70. - PMC - PubMed
    1. Antoniades C, Shirodaria C, Van Assche T, Cunnington C, Tegeder I, Lotsch J, et al. GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function. J Am Coll Cardiol. 2008;52:158–65. - PMC - PubMed
    1. Chen DD, Chen LY, Xie JB, Shu C, Yang T, Zhou S, et al. Tetrahydrobiopterin regulation of eNOS redox function. Curr Pharm Design. 2014;20:3554–62. - PubMed
    1. Furukawa Y, Kish SJ. Parkinsonism in GTP cyclohydrolase 1-deficient DOPA-responsive dystonia. Brain. 2015;138:e351. - PMC - PubMed
    1. Furukawa Y, Nygaard TG, Gutlich M, Rajput AH, Pifl C, DiStefano L, et al. Striatal biopterin and tyrosine hydroxylase protein reduction in dopa-responsive dystonia. Neurology. 1999;53:1032–41. - PubMed

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